Metabolic pathway activity estimation from RNA-Seq data

نویسندگان

  • Yvette Temate-Tiagueu
  • Meril Mathew
  • Igor Mandric
  • Qiong Cheng
  • Olga Glebova
  • Nicole Beth Lopanik
  • Ion Măndoiu
  • Alex Zelikovsky
چکیده

An interesting approach to study the metabolic differences between species is metabolic pathway. In this study, we characterize pathways activity levels of two samples. We applied our proposed methods on RNA-Seq Bugula neritina metagenomics data. We successfully identified several differential pathway activity and we selected 3 of them for qPCR validation.

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تاریخ انتشار 2015